Chapter 143 Biochemical Analyzer
Molecular-scale cell models are something that biological laboratories in various universities have been working hard to establish and improve.
Two hundred years ago in the 21st century, around 2034, the number of molecular-level biological models possessed by universities and research institutes in China was.
The existence of biomechanics laboratories does not exceed seventy years. Even in China, the earliest and most abundant cell models were not produced in biomechanics laboratories.
However, the ascidian model in their laboratory is brand new and sophisticated enough. Because it is young, it is advanced. It is not only a cell model at the molecular scale, but also a model of the entire organism at the molecular level.
Lanze, the model builder, boasted that he could use the accompanying computing tools to make any functional modifications to ascidian cells. As long as the corresponding DNA sequence is calculated using biochemical rules and embedded into the original chromosome, the modification can be heritable.
.
What the existing DNA design laboratories do is to use gene banks to assemble the DNA of new cells. The ones that do well are those that have accumulated relatively strong gene banks.
"You are so awesome!" the fairy said.
Professor Luo specially called all the laboratory staff, including those who were busy, those who were idle, those who did odd jobs, and those who came in for a walk, to hold a meeting.
He announced to the world that the laboratory's ascidian mathematical model and ascidian data dynamic library are ready for use. Colleagues are welcome to come, either to worship or to destroy the place.
This meeting is open and the door is not closed.
The fairy waited until the meeting was over before coming in to find Lan Ze.
Lan Ze was surrounded by a group of juniors and juniors, all of whom had worshiping stars in their eyes. He used to play simulators in the sports hall, and he was often worshiped, so he was quite used to it.
"It's not bad." Lan Ze said without humility.
"If cells can be modified, how can we modify it if we don't know what gene corresponds to its function?" asked a senior junior in the mixed laboratory who is studious and inquiring.
"Forget it."
"What's that?" Junior Sister looked cute.
"Use functional proteins to calculate DNA." Lanze said matter-of-factly.
"Hey? Can we program?" The fairy suddenly realized.
Lan Ze pondered for a while and said, "That's a good idea."
As soon as the fairy said it, he realized that using intermolecular forces to back-calculate DNA sequences was basically programming!
He is very familiar with computer programming. Although he has never played with DNA sequences, the principles are roughly the same, with slightly different rules. As for the two ends of the same chromosome communicating through resonance, long DNA chains are adjusted in various twists and turns.
The functions and characteristics of these biological macromolecules are interesting because they are not exactly the same as computers. Isn’t it?
Upstairs in their laboratory, as well as in the research institute of Dadong R&D City, there are people doing DNA programming and design. Many laboratories can make some modifications with special functions based on existing eukaryotic microorganisms. As for virus design,
There are already a small number of mature commercial applications.
The comparison table between DNA and amino acids was figured out as early as the 20th century. It is completely impossible to design living things based on this alone. Just like knowing that iron is iron, we are still 800 miles away from inventing the stapler.
Most of the content of the gene library is actually about how the activities in cells are controlled and operated under various conditions. It is based on the so-called "operator". Most of the components of the operator are not arranged in order.
.Sometimes it can even span several chromosomes. It is precisely because of this complexity that every new functional unit in the gene pool needs to be analyzed very carefully. The accumulation of gene pools has been very slow in history.
Without a gene bank, there are no parts for DNA programming.
Lan Ze suddenly felt that he could do something more. For example, write a biochemical analyzer to replace the gene bank?
It should be possible to calculate various life-related control methods and various functional macromolecules, right?
Thinking of it, he asked:
"Do you guys have time to help me do some verification experiments?"
"Senior Brother Lan, what experiment are you going to do?" A group of junior fellow students rushed forward enthusiastically, "I'll come, I'm free."
"Don't worry, the experiment is enough for everyone to share." Lan Ze said calmly.
"How can I help?" the fairy asked with a smile.
Lanze thought for a while: "I want to see what the existing biochemical analysis algorithms look like."
The fairy screened some commonly used biochemical analysis algorithms for him that were not confidential.
After Lan Ze returned to the dormitory to receive it, he lay on the bed and read it slowly. It was already quite late.
One thing he discovered was that these algorithms were quite old.
Physics and mathematics are not subjects that have not progressed for hundreds of years. But these algorithms are based on human understanding of the world hundreds of years ago.
As a person who feels he is good at mathematics, Lanze believes that he should rewrite the biochemical analysis algorithm himself.
Existing algorithms are not suitable for analyzing biological macromolecules. Especially large, complex long chains of polypeptide chains, ribose chains, and polypeptides combined with ribose, which often have knotted and twisted structures.
These structures are the basis of many biological functions. However, some of the existing algorithms have no essential difference from arithmetic, and some do not care about these complex structures at all.
The reason is simple: there are specializations in academic fields. Mathematics, physics and chemistry are inherently different fields.
Mainstream algorithms have been tested for a long time and are generally simple and easy to use without being too advanced. However, when used to deal with biological microscopic activities, the efficiency and accuracy of these algorithms are not enough.
As for the secret-level biochemical analysis algorithm treasured by the national research department, Lan Ze cannot yet see what it will look like.
After he finished pondering these existing algorithms, he closed his eyes directly and planned to go to sleep. A flash of blue light seemed to flash in the corner of his eyes.
So he raised his bracelet and took a look and found that there was a delayed message.
He had set it up to contact college sister Zhang He, and the bracelet flashed blue.
"Kids, do you want to go swimming?" Sister Zhang's voice was particularly textured. It wasn't crisp, but it sounded nice.
This message, according to the college lady's settings, should have vibrated to remind him to check his bracelet after he woke up, but now he can check it in advance.
"Think." Lanze replied softly.
"Hey? What time is it? You still don't sleep?"
"Can't sleep." Lan Ze closed his eyes. He was telling lies with his eyes closed.
"Can't sleep, let's chat for a while?"
"don't want."
"Um?"
"Come on. When are you going to swim?" Lan Ze asked in a daze.
"Swimming..."
"Say the time." Lan Ze was very sleepy and wanted to go swimming. Regardless of whether he could swim or not, just looking at the water would be good.
Chapter completed!