669. Report truthfully – polish
Siphon is 62 years old and is still sitting in the seat of Director Niaid, as stable as a rock.
The age of 62 is already considered retirement for other doctors, but not many traces of time left on Siph. His energetic appearance and unique appearance conditions make him full of the charm unique to middle-aged and elderly men.
Of course, the melancholy unique character of Italians also had a profound impact on Siphere.
Especially after he served as the director of niaid, the old man's face was no longer smiling. This time the development of North Carolina's love made him worry for several days.
If it were a common epidemic infection, Siphre would not have anything to worry about, and he wouldn't even need to worry about it.
However, North Carolina's situation has become so serious that CDC attaches great importance to it. The traceability investigation report for reporting the information was written in a full 200 pages. He, an infectious disease scientist and national public health consultant, naturally cannot worry, and must write a virus research report.
The report itself is not difficult. The cause, process and result are all placed in Syphus's head. You can finish it by typing on the keyboard. But the difficulty lies in that the keyboard is not completely in his hands. Director Niaid's power is still small after all, and sometimes he still has to play the tacit understanding card.
Give others a way out today, and they will be polite to you tomorrow.
Just half an hour before Qi Jing called, Siph had been sitting in front of the computer screen for a long time.
The report in front of him was deleted, and he wrote it down, and he went back and forth several times. The details and words were repeatedly changed several times, but he could not produce a final version.
[At 10:33 on August 12, 2008, the Center for Disease Control and Prevention, which belongs to Poke County, North Carolina, received a report from the town hospital that the hospital's respiratory department admitted a case of severe pneumonia in a coma and was in a critical condition.
The patient died of ineffective rescue on the morning of August 13.
The Centers for Disease Control and Prevention did not detect common influenza virus from the tracheal secretions of the deceased before his death...]
This is just the beginning, but the number of letters and words that are typing back and forth has long exceeded the number of words that should be reported, and Sipher has never been able to grasp what he wants to express next.
From the facts, because the flu was not detected, the local CDC actually did not take this patient seriously. There are too many people who die every day, and pneumonia is also a common disease. Among all pneumonia, only influenza needs statistical reporting.
So as long as it has nothing to do with the flu, there is no need to record it.
But then the number of cases increased day by day, and Lehn's CDC reported the matter to the state CDC.
But the reporting time has been two weeks since the first case died. From August 13 to 28, what should I do if I did the 15 days in the middle? If I just wrote the original words on, even a fool would find the problem.
Besides, the people who come to him as consultants are all humans, so how could there be fools?
Sipher thought about it for a long time and decided to polish it:
[After the discovery of the first "case of pneumonia due to unknown cause", the county government immediately launched testing and raised Leen Town to a medium-risk area to restrict entry and exit.
Due to limited local conditions, the state CDC finally intervened and applied to send a research team to the University of North Carolina to conduct laboratory examinations after conducting laboratory tests, and the influenza virus H1 nucleic acid was positive. Four days later, the virus serotype was measured as h1n1, which is highly likely to be derived from swine influenza.
Since the 12th, the situation has been controlled in Lehn Town, and the state cdc has not applied to declare a state emergency.
Because the specific time has been hidden, the whole sentence seems to have fewer edges and corners, and it has also helped others to clean up a lot of bad things, which can be regarded as the perfection of imperfections.
Although he, a scientific worker, felt uncomfortable looking at the bare letters, he still had to do the storefront skills to "protect" his several old friends and brothers' departments.
Who asked the reporting materials prepared by cdc to be written like this?
Thinking that the love was over, Siphre didn't think too much, and it was not impossible to help with the investigation process.
[The first patient developed symptoms of headache and dizziness on the evening of August 3, and had a fever of 39.9℃ early on the morning of the 4th. After resting at home for two days without improvement, the patient rushed to the town hospital on the 6th for treatment. The symptoms were dry cough, headache and dizziness, muscle pain and fatigue throughout the body.
On the evening of the 7th, the patient developed shortness of breath, and the chest radiograph showed "lower left pneumonia", and had difficulty breathing on the morning of the 8th.
That night the patient was transferred to the ICU, on the ventilator, and diagnosed with "severe pneumonia". The CT review on the 9th showed "diffuse ground-glass-like changes in both lungs, diffuse pneumonia?" On the 10th, he convened experts from the respiratory department of North Carolina State University Affiliated Hospital to consult: 1 severe pneumonia in both lungs; 2 acute respiratory distress syndrome...]
Siph originally wanted to write down the laboratory results, but after thinking about it, he deleted them. Instead of wasting this space, it would be better to focus on his own testing research results. (1)
However, hospital examinations can be avoided, but specific epidemiological investigations cannot be missed.
[The first deceased was a resident of Lehn Town, 38 years old, and was in good health. In 2002, he suffered from influenza pneumonia and recovered after one week of treatment in the outpatient clinic. He had no history of influenza vaccination, no clear history of contact with birds and animals, and had no history of traveling 14 days before the onset of the disease.
The deceased ate and lived with his parents during his lifetime, and both of his parents have retired and were at home.
On August 9, the deceased's father developed similar symptoms, such as dry cough, high fever, and muscle pain throughout the body. On August 13, the deceased's mother also developed similar symptoms, and the two were admitted to Lehn Town Hospital together.
The test results of transtracheal secretions samples showed that they were all h1n1 influenza viruses, which were highly homologous to the infected strains of the deceased.]
At this point, the whole spread of emotions was normal, and Siphon wrote very smoothly, and there was almost nothing to hide along the way. But the subsequent diffusion stage became more magical. He took the materials given by CDC and then began to use the keyboard at hand.
[The deceased had three girlfriends. CDC tested them and found that all the h1n1 nucleic acids in the three were positive. A and C had mild symptoms, and the onset time was August 10 and August 14, respectively, which were specifically manifested as ordinary upper respiratory tract infections, such as sore throat, cough, low fever, etc.
However, there were no obvious symptoms and was the first asymptomatic infection in Leon Town.
My girlfriend a lives alone, and another male friend who has had close contact with her, and the nucleic acid test was negative; b lives with two old classmates, and another female friend has close contact with her, and all three of them have negative nucleic acid; c......]
Sipher gasped, stayed on the large section of data after c for a while, took another sip of coffee, and then wrote:
[c is an xing worker. From 14 days before the onset of the disease to the test, a total of 24 men were received, all of whom were tested for nucleic acid. Among them, 13 positive, and the rest of the negative, including those who had previously had close contacts, were isolated.
13 positive people traced the origin again...]
There are more than 20 pages of the tracing report of CDC alone. Sever's work actually has nothing to do with tracing the source, but as a functional department of infectious diseases research, tracing the source itself is also a research project. The infection model can be simply calculated from the tracing, and the risk level of the infection for the superiors is to judge this time.
Therefore, this kind of simple traceability report is very necessary.
His real main business is still in sample testing.
[There are 197 positive cases of nucleic acid, 48 false negative cases, 18 severe cases, 2 deaths, and the first death case reported and their mother. During this transmission of nucleic acid, no medical staff were infected.
The research team detected positive influenza h1n1 nucleic acid from tracheal secretions in several positive cases, and also positive results were found in blood samples and pharyngeal swab samples. The h1n1 virus was isolated on the fifth day after Niaid entered the lab of the University of North Carolina on September 28, and cracked the virus gene sequence on October 27.
This is a brand new flu virus.
Judging from the genetic sequence, the new virus is not closely related to the known human influenza virus, but is very close to the known swine influenza virus. Its homology is more than 90%, so it should belong to the swine influenza virus.
Among the 8 gene fragments in total, 6 gene fragments are from swine flu viruses, and the remaining 2 fragments originally belong to human influenza viruses and avian influenza viruses respectively. However, compared with the typical swine flu that spreads between pigs, it contains more lysine and has faster mutation speed...]
The above are all the research results of Niaid, but for his superiors, it is not important whether the gene sequence developed by Niaid, whether the virus will mutate or the nearly 200 cases that have occurred.
What is important is whether the new virus will spread further to other towns, will it cause widespread nationwide, and where its earliest source is.
These are actually CDC jobs, and according to their reporting documents, it is almost impossible to spread. But Lehn is a small town with a population of nearly 10,000. The dry climate in North Carolina is very suitable for tourism in late autumn, and the risks increase exponentially. To say that it is impossible to spread is simply a release.
But as the director of Niaid, who focuses on research, he cannot say much, and can only do his part in the tracing of the source.
[Considering that the virus is a mixture of three influenza: pig, bird and human, the pig's respiratory epithelial cells have receptors for human influenza virus and avian influenza virus, and are the common susceptible hosts of pig, bird and human influenza virus.
Therefore, the niaid research team focused on pig farms and raw pork flowing into the market.
There are 13 meat-related markets in Lehn Town, 8 pork-related markets, of which 5 are related to positive cases. No h1n1-related antibodies were found from the raw pork in the 5 meat markets, and all tests for meat market practitioners and transport vehicles were negative.
There are three pig farms within 50km of Lehn Town, two of which have undergone systematic testing and no virus was found. The last one can only be tested by the Institute of Infectious Diseases of North Carolina State University because of the relevant agreement signed by the owner and North Carolina State University, and the result is also negative...]
As the report was written, Qi Jing's phone suddenly called in, cutting off Siphros in half.
So at the beginning, the old man was very cold to him, until he talked about the pig farm and then talked about the swine flu, which surprised Siphon and even frightened him.
Because in fact, Morton's pig farm was tested by the North Carolina State University Institute of Infectious Diseases. If the owner is really infected with the swine flu virus, it means that the entire test result is fake.
This not only includes all the pigs on the farm, but also the Morton family as staff.
Of course, the possibility of false negatives is not ruled out, because during more than a month of work, their research team found that the probability of false negatives in h1n1 test is as high as 25%. But this is also the focus of Niaid's attention when handing over the work to the other party. Even if a negative result occurs, it will take seven days to review it.
Only after a review can the final result be judged, and the possibility of false negative after a review is approximately 0, at least his group has never seen it.
On the other end of the phone was a young man who had just come from China, did not have a US medical practice certificate, and was under 30 years old. The folder on his hand was a state university in the Infectious Disease Research Laboratory with several professors. Whether it was reputation or academic research capabilities, this Chinese had no advantage.
Moreover, the United States is now in the flu season, and it is normal to have a headache and fever influenza symptoms.
No matter how you look at it, it should be Qi Jing’s wrong judgment.
After considering these, the patient should be ordinary flu.
But Siphon listened to Qi Jing's speech there. In addition to the test report of this pig farm, there was also a report from CDC to him. This time, he saw CDC's "ability" to deal with his mistakes. Even the state-owned departments can do this. It seems reasonable for a university laboratory to make mistakes.
In the early stage, the method to distinguish this new H1n1 influenza virus from ordinary influenza was only at the rate of invasion of the lungs except nucleic acid testing.
If pneumonia occurs early in the onset, and there are flu-like symptoms, and the distance between them and Lehn Town, it is not an exaggeration to suspect that this pig farmer is a fish that misses the net. So it is very important whether Morton has pneumonia. If it is really confirmed that it is pneumonia, Siphre will no longer have the idleness to report it.
"I said just now, I just heard the wet rosy. I personally think the possibility of pneumonia is very high, but in the end I still like to go to the hospital for a check-up before I know."
Qi Jing's words were very official, almost comparable to the things she said in a formal workplace. Xu Jiakang felt strange at first, because Qi Jing basically insisted on her verbal words when she was diagnosed, but why did she suddenly become cautious today?
He thought about it for a long time but couldn't figure it out until Qi Jing hung up Sif's phone and talked to Ji Qing about the situation at Morton's house again, and then he figured out the whole story.
Xu Jiakang secretly auscultated Morton beside him. Although the rumbling noises of pickup trucks were everywhere, he was very sure that Morton had no wet rhombus at all. Thinking of some things before, he suddenly realized: "Are you bluffing us just now? He was just..."
However, Qi Jing is not in a mood to chat now: "It doesn't matter whether he has pneumonia or not. The key problem now is that he is pregnant with his wife, Ji Qinggang's body temperature measured by 38.1℃."
Chapter completed!