[On duty today, a little busy, 615 has been changed and lifted tomorrow's ban]

Recently, jama    psychiatry and nature’s molecular     psychiatry have published articles, exploring the relationship between late sleep and mental health, especially depression disorders through a large sample study of as many as hundreds of thousands of people.

molecular       A paper on late sleep and mental health published by psychiatry

Your sleep time may not meet your physical needs

In the millions of years of evolution, in order to adapt to the natural circadian rhythm, the human biological clock will oscillate within a corresponding period of time (such as about 24 hours). Our body metabolism—including neuroendocrine—will operate according to this biological clock, such as secreting a certain hormone or releasing a certain chemical factor at a certain period of time to help or encourage us to complete neural activities and other metabolic activities.

At this level, current research has found that there are two types of biological clocks in humans, one is the "lag" type when going to bed early and getting up early, and the other is the "night owl" type when going to bed late and getting up late. The biological rhythm of the former is closer to the natural rhythm and is not much different from the normal sunshine cycle. The biological rhythm of the latter is longer, resulting in a phase difference with the natural rhythm, which is easy to cause some problems.

Of course, the rhythm of the "night owl" type is not exaggerated until it is hiding at night or is still jumping around at two or three o'clock in the middle of the night. Current research has found that in general, the phase difference between the late-sleeping type and the early-sleeping type is about 2 hours. Therefore, if you don't sleep at two or three o'clock in the middle of the night for a long time, it is not because the circadian rhythm is night owl type, and it may have serious biological rhythm abnormalities and need treatment.

In addition to biological rhythms, in the contemporary society with large-scale electrification, there is also a social rhythm. The widespread night light has greatly extended the original natural light time, and the rhythm of sunrise and sunset in the past has been disrupted. This state causes a time difference between biological rhythms and social rhythms. Such a time difference has led to a considerable number of sleep problems, especially for those with late-sleeping rhythms.

People with a rhythmic rhythm of going to bed better mental health

jama       The two studies published by psychiatry and nature                                                                                                                  

In the study of jama    psychiatry, the researchers conducted statistical analysis through 840,000 sample data from two large gene banks and found that people with early sleep genes have a 23% lower risk of depression disorder than the average level. Statistics show that every 1 hour earlier in the sleep time of these people (the median sleep time point of the entire population in the study was 3 o'clock, and the average sleep time period was 11 o'clock at night to 6 o'clock the next morning), and the risk factor could decrease to the original 0.77 (95% confidence interval: 0.63-0.94). After the researchers narrowed the study sample to patients diagnosed with major depression disorder (mdd), this trend still worked.

The study of this article concluded that people with early sleep type genes have a lower risk of developing mdd.

In the study of molecular    psychiatry, this conclusion was further refined. In this study, the researchers surveyed 449,660 gene database samples, of which 62.6% were early-sleeping type. In this study, the characteristics of the early-sleeping type population were shown to be female, with lower bmi and fewer smokers.

Researchers found that compared with those who went to bed early, the risk of depression symptoms was 0.79 (95% confidence interval: 0.77-0.81), the risk of depression disorder was 0.84 (95% confidence interval: 0.82-0.88), the risk of depression disorder was 0.84 (95% confidence interval: 0.82-0.88), the severity of depression disorder under the patient's health questionnaire (patient         questionnaire, phq)9 diagnostic criteria decreased, and the risk of generalized anxiety disorder (generalised      disorder, gad) was 0.83 (95% confidence interval: 0.79-0.87), and the severity of anxiety disorder was also decreased.

In other words, people who go to bed early have lower risk of depression and anxiety than those who go to bed late, and their severity is lower after the disease occurs.

Another study found that people with late sleep have a higher risk of schizophrenia and adhd.

Why do people who sleep late have high mental health risks?

A late-sleeping bio-rhythm has a longer rhythm than a natural rhythm, that is, if you want to adapt to your own biological rhythm, your daily routine will cause a certain amount of dislocation from the natural light rhythm. At the same time, the natural light rhythm affects human metabolic regulation.

In other words, there is a contradiction between the biological rhythm and the natural rhythm of late-sleeping rhythm, unlike those of early-sleeping rhythm, which basically matches the natural rhythm. Under this dislocation, the mental health risk factors of late-sleeping rhythms have already increased.

The current social rhythm generally requires early waking up, which is more suitable for the needs of early-sleep rhythmic people, which force late-sleep rhythmic people to get up early, forming a forced time difference, and even serious sleep deficits, forming sleep debts, leading to sleep disorders, various emotional disorders and even mental illnesses. If late-sleep rhythmic people try to make up for sleep on weekends and repay sleep debts, it will further lead to rhythm disorders in the subsequent working days. Researchers found that late-sleep people who make up for sleep on weekends can have a 3-hour difference with working days, and the sleep time is much higher than that on weekdays.

The time difference between social rhythm and biological rhythm in late sleep can reach 3 hours

Fortunately, among the total population, the number of people who go to bed early is relatively large, and as age changes, the biological rhythm of humans will change. Some individuals who are late-sleeping in adolescence or adolescence will gradually turn to early-sleeping after age. Studies have shown that men account for a higher proportion of people who go to bed late, so the total population statistics show that men usually sleep later than women, but this difference will disappear after the age of 40-50.

However, for early-sleeping people, if they are forced to go to bed late, they will also have the risk of mental health damage.

At present, it has been observed in clinical practice that interruption or disorder of sleep and biological clock will lead to a decline in cognitive function, and the advanced executive functions such as alertness, attention, memory, reaction ability and decision-making will be damaged. Impaired circadian rhythm will affect neurometabolism, leading to changes in the rhythmic activity of the neurotransmitter system involved in emotional regulation, thereby causing emotional disorders. Some mental illnesses, such as depression disorders, anxiety disorders, schizophrenia, etc. are highly correlated with insomnia, which will in turn further damage the circadian rhythm and sleep rhythm, further affecting neuroendocrine, causing vicious cycles and aggravating the disease.

The sleep survey results released by the China Sleep Research Association in 2016 showed that the incidence of insomnia in Chinese adults was as high as 38.2%, and more than 300 million Chinese people had sleep disorders, and this data is still rising year by year. A study published in Lancet psychiatry in 2019 showed that the lifelong prevalence of mental illness among Chinese people was 16.6% (95% confidence interval: 13.0–20.2). Although relatively low, in the face of a huge population base, the number of patients was huge, reaching more than 230 million. Among them, the lifelong prevalence of anxiety disorder was 7.6% (95% confidence interval: 6.3–8.8), and the lifelong prevalence of depression disorder was 6.8% (95% confidence interval: 5.8-7.8), both of which were around 100 million.

Mental health has a great relationship with the environment and human behavior. How social rhythms should be more adapted to the biological rhythms of the population to protect the health of most people even exceed the huge topics in the scope of medicine.

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In front of the self-service registration terminal of a hospital in Beijing, Mr. Wang was skillfully selecting the medical services he needed. In just a few minutes, the registration receipt containing medical information was printed out from the terminal.

Uncle Wang is an old patient in the gastrointestinal department of the hospital. With the continuous development of medical services, he deeply felt the convenience brought by technology. Looking back on the medical treatment process many years ago, Uncle Wang was filled with emotion: "In the past, I had to queue up to register at the hospital very early, because the registration and payment processes required medical personnel to complete them manually. It not only took time, but also made mistakes in information registration. You see, now, just choose one on this small machine and click a little bit, and the registration process will be completed in a few minutes. It is fast and convenient!"

As technology becomes more and more mature, more and more medical institutions are increasing their efforts to use information technology to improve medical experience and improve medical service levels. Practice has proved that the integration of technology and the industry has not only effectively improved the level of medical service, but also provided strong support for medical institutions to gain a long-term development.

The outbreak of the new crown epidemic has brought unprecedented severe challenges to the medical industry.

In order to ensure effective prevention and control during the epidemic, hospital door and emergency services have been adjusted and controlled accordingly, but it also has caused many difficulties for patients to seek medical treatment. Remote technology has become the key to solving the problem - remote consultation, remote film reading, remote consultation, remote surgery and other applications have greatly improved the medical service capabilities. While effectively reducing the risk of cross-infection in the epidemic and protecting the safety of doctors and patients, it provides patients with a better and more efficient medical experience.

However, the implementation of various functions of telemedicine services has extremely strict requirements for medical terminals: in the process of remote surgery, film reading, consultation and other services, the terminal's rapid response and smooth operation are all prerequisites to ensure the smooth progress of telemedicine services. Especially in scenarios involving medical images, traditional terminals may easily experience lags, delays and other problems due to insufficient computing power have seriously affected the quality of medical services and even endangered the health of patients in serious cases. This means that traditional medical terminals have difficulty coping with the ever-enriching medical needs.

In the face of the above difficulties, how to ensure the smooth progress of telemedicine services? Intel?vpro? platform was born. This platform can bring business-level performance and hardware-level protection to terminal computing devices, making it modern manageability including out-of-band remote management. Even if it carries a large number of PCs, it can ensure business continuity. While ensuring terminal business efficiency, it greatly simplifies IT management and gives doctors a "great potential" to do.

Although the current medical situation in my country still has problems such as insufficient resource allocation and difficulty in seeking medical treatment, with the rapid development of the industry, my country's medical model has undergone tremendous changes and medical service capabilities have also been greatly improved. There is no doubt that the continuous integration of technology and the industry has given medical services more "possible":

1. Operation and maintenance deployment zero contact to help epidemic prevention and control be carried out efficiently

After the outbreak of the new crown epidemic, a Huoshenshan Hospital with a total construction area of ​​33,900 square meters and can accommodate 1,000 beds was officially delivered on February 2, and the construction was completed in a total of 10 days. On January 25, the Wuhan government built another "Leishshan Hospital" and was delivered and used on February 5. The construction progress of the two hospitals calculated in hours has demonstrated the speed of China in the new era under the gaze of attention.

Among them, Leishenshan Training Center and the square cabin hospitals have deployed idv solutions built on the Intel ?vpro? platform. With its superior centralized management capabilities, contactless operation and maintenance are achieved, helping IT managers quickly diagnose faults, realize virtual layer repair and maintenance, and complete the rapid installation and deployment of terminal equipment and printers. While reducing the risk of infection, it effectively improves operation and maintenance efficiency, providing strong guarantees for the smooth development of epidemic prevention and control work.

2. Excellent management, realizing manpower and time savings

In fact, not only during the epidemic, even during the daily operation and maintenance of IT, the large number and complex needs of terminals still bring great challenges to the hospital's information department. How to deal with these challenges?

Faced with the current situation of complex network environment, numerous systems and difficult management brought about by the rapid development of the hospital, many hospitals realize that it is urgent to improve the daily operation and maintenance of the network, management capabilities, and operation and maintenance management efficiency. Under this situation, the PC equipped with the new Intel VPro platform can realize the remote management of computer equipment and systems of various departments of the hospital through active management technology. This means that the department no longer has to send a large amount of manpower to solve the problem by sending a large number of manpower to each problematic computer. It only takes a few people to easily maintain hundreds or even thousands of computers, effectively saving human resources and time costs.

It has been learned that through the vpro platform, you can effectively get rid of your dependence on the operating system. As long as you have a network and power supply, even if the terminal is in a shutdown state, you can still realize remote diagnosis, remote boot, remote asset management and other functions.

3. Quick response and continuous stability, empowering high-quality and efficient medical services

The birth of new medical services such as self-service registration, Internet diagnosis and treatment, and telemedicine has made the application of medical terminals more and more widely. Given the particularity of the medical industry, terminal stability and rapid response capabilities are directly related to the efficiency and safety of diagnostic services, and are an important part of ensuring the smooth progress of medical processes. Therefore, medical terminals with rapid response and strong stability have become the key to meeting the increasingly complex medical service needs at present. Based on this background, what should hospitals do?

As the demand for medical services continues to rise, the scale of many hospitals is also expanding, and more and more new campuses are built. Many hospital information managers have said that if there is no efficient IT terminal management solution, there will be many difficulties in computer management in the new campus. The number of engineers in the hospital is usually not very large. Taking four people as an example, according to the average time for each person to complete daily maintenance work of each PC, 1,000 computers is 500 hours, and each person works 8 hours a day to complete 8 days. Even if you don’t sleep and work 24 hours a day, it will take 6 days to complete, which does not include wasting time on the way. At that time, the solutions for enterprise IT terminal management in the market were still blank. If traditional methods were used to solve the above problems, it would be impossible to complete.
Chapter completed!