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387. The murder (1): armed

At 4:25 am on October 14, Huang Yuhuai walked into the gate of the International Convention Center with a trendy black sports carriage accompanied by his son's assistant.

The assistant followed him, his face gloomy and gloomy.

She knew that the old man had a stubborn temper, but Huang Xinghua also gave a death order, and it would be fine if he disobeyed any side. After thinking for a while, the assistant made up his mind and reiterated the suggestions he had just said: "Teacher Huang, please take them for me, it looks very heavy."

Huang Yuhuai is 1.8 meters tall, half a head taller than the female assistant. At the age of 70, he is far from being able to walk like a flying stroll, but it is also enough to be able to be fast: "No, this jansport backpack has just been bought for a while, and I feel at ease with my back."

The assistant was a little embarrassed: "But Director Huang said that your back and back are not good, so I'll take it."

Huang Yuhuai looked back at her, stopped suddenly, and raised his index finger in front of his mouth, and shook his head at the same time.

Seeing him like this, the female assistant knew that she was angry, so she had to shut her mouth and bring the topic to this case: "Now the expert group found by Director Huang is divided into two groups, one group of infectious disease experts in the conference room on the 3rd floor, and one group of critical shock treatment experts in the fax room on the 1st floor."

“Fax room?”

"Well, I'm afraid that Yunchuan will not be able to explain the patient's condition clearly, so I hope to send the report by fax." The assistant worked by Huang Xinghua for several years. Knowing what the old man is thinking now, he immediately pointed to a corridor next to the hall and said, "The fax room is there."

"Let's go to the fax room first."

Huang Yuhuai was thinking about the case his son mentioned along the way. Judging from the symptoms, all aspects were perfectly consistent with the bacteria he thought of. What we need to do now is to verify, and at least two questions must be asked first, one is whether there is hearing loss or loss, and the other is whether there is cold sores.

If you have these two symptoms, you can basically conclude that it is the bacteria. If not, it may take some brains to do so.

Of course, if not, considering the possibility of human-to-human transmission, Huang Yuhuai is ready to leave for Yunchuan at any time. Anyway, he has now removed a lot of burdens, and there is only an academician on his shoulders. He stopped taking students several years ago, and there are also people in the research team in his hands who are taking care of him and he doesn't need to worry about it.

As the saying goes, without an official position, he is ready to enjoy his "life joy" in the final stage of his life.

Wang Gui's treatment is also an important part. Now, the antibiotics have been developed, and it is basically the top match in 2005. In terms of shock, Yan Hong, one of the best shock treatment experts in East China, is in charge. Wang Gui's situation should not have any major problems.

But Huang Yuhuai was still worried.

He knocked on the door of the fax room and glanced at the eight doctors sitting around in the distance: "How is the patient's condition?"

"Old Huang, why are you here?" Several old experts, including Yan Hong, stood up and greeted him. "How did Director Huang move you here? How could he bear it when he stayed up late at such an old age?"

"Anyway, I'm idle, I'm idle. I usually get up before five o'clock, so it's nothing serious."

Huang Yuhuai's gaze immediately fell on Ji Qing, who was standing at the end of the crowd, and compared it with the figure in his heart, almost instantly eliminating his suspicion: It seems that the boy is not here.

"Let's talk about the patients first."

Although Wang Gui has received sufficient treatment, and both antibiotics and current treatment teams have reached the best level, overall, his condition is not optimistic. Wang Gui is now in an awkward stage, like a car that is stepping on the brakes, which can significantly slow down, but still has to continue to slide forward due to inertia.

"The blood pressure was maintained at around 9045, but the heart rate was not lower, but it was higher than before." Ji Qing took on the burden of reporting, "now it was maintained at around 125."

"After such a heavy dose of dopamine, the systolic blood pressure did not return to above 100..." Huang Yuhuai looked at the treatment record list in his hand and asked, "Is Wan Gu hung up?"

"Well, I just lost a bag and the effect is good." Ji Qing said, "I checked my blood routine and the infection did not continue to worsen."

"It's natural that the effect will not be too bad. But it has barely stabilized the blood pressure, but the heart rate has not dropped yet. Have you ever considered other reasons?" Huang Yuhuai immediately hit the key point, and the angle is much wider than that of the others here, "For example, the side effects of vancomycin."

After saying that, under the surprised gaze of a group of people, he took the cell phone handed over by Ji Qing: "Lin Rong? Where is the person?"

It seemed that the person's voice had long been heard on the other end of the phone, and he did not dare to neglect it. He immediately replied with a smile: "Old Huang, I am here, do you have any instructions?"

Since Wang Gui entered Licheng's disease control, Lin Rong's level has been surprising. When he worked at Huang Xinghua's research institute, he was at least half a student of Huang Yuhuai. Now this look really makes the old man feel disappointed.

However, for the sake of the patient, Huang Yuhuai was too lazy to waste time and scolded him, and just said: "Look at the patient's skin."

"skin......?"

Lin Rong took his cell phone, approached the hospital bed, lifted the quilt, and found that a rash appeared on the chest connected to the ECG monitoring. This was not a petechia caused by infection and shock, but a very typical urticaria. Looking at Wang Gui's neck and upper limbs, the skin of this rash was already covered with this kind of rash.

Before, because I was covered with a quilt and had a breathing mask on my exposed face, no one noticed it.

"Old Huang, it's allergic to urticaria!"

Huang Yuhuai couldn't help frowning when he heard this.

At this time, Ji Qing's reaction was fast enough and quickly explained: "Vancomycin allergies are very rare. This should not be an allergic, but a toxic side effect of vancomycin, similar to the Red Man Syndrome of allergic urticaria."

After hearing this, several experts around nodded slightly. Huang Yuhuai also raised his eyebrows and looked over: "Lin Rong."

"I, I'm..." Lin Rong heard the words "Red Man Syndrome" and immediately recalled the definition of this disease. He was embarrassed and speechless for a moment and couldn't say a word.

"A doctor of infectious diseases doesn't even know the characteristics of the weapon in his hand." Huang Yuhuai looked Ji Qing up and down and continued, "I can't compare to a young doctor who is a doctor who is in the internal medicine for emergency treatment. He is getting back and forth."

Lin Rong wanted to cry without tears.

He did know about this Red Man syndrome, but that was also ten years ago when he was in the institute. After coming to Belvedere, he had never touched vancomycin. This shallow memory had long disappeared in a relaxed and comfortable life. It is not easy to remember it at the first time.

Lin Rong knew about Huang Yuhuai, and at this time the rebuttal would have a negative effect: "I was not considering it carefully and missed this situation."

"There is no use in the ages." Huang Yuhuai looked at the treatment record sheet in his hand and sighed, "Tai Neng may not be of much use to Gram-positive bacteria, and it is troublesome to treat it."

"Hal has Huang Lao confirmed the bacteria?"

"It's almost the same." Huang Yuhuai looked at the ceftriaxone and levofructose that had been ineffective in the treatment before, and suddenly he was one and two big. "Now the patient's cause is almost the same, and the shock has been held down. It's useless to guard the fax machine. Go back to the third floor with me and discuss the next medication strategy together."

"What specific bacteria is it?" Ji Qing asked after looking at the text message he had just sent.

Huang Yuhuai was willing to continue hiding. He looked back at him and said, "Streptococci, a zoonotic disease."

"Streptococci?"

"I've never heard of it."

“Where did it come out?”

"Don't talk anymore." Huang Xinghua looked at them in surprise and suggested again, "Let's chat again when you go back upstairs."

"good."

Although this bacteria is rare, Huang Yuhuai has had two dealings with it in the country in recent years. The impression he left was two points: the course of the disease is rapid and the drug resistance is strong.

Based on his understanding of Streptococcus suis, diagnosis is only one link, and treatment is the troublesome place.

......

"Diagnosis is only one part, and then treatment is the troublesome place." Now there is no idle in the 3i conference room. Qi Jing had just diagnosed Streptococcus suis infection, and before the experts present were taking a breath, he continued, "There are too many subtypes of bacteria, some of which are low in drug resistance, while others are very resistant."

"Is it Gram-positive bacteria?"

"right."

"Then vancomycin doesn't work?"

"There are also vancomycin-resistant." Qi Jing glanced at everyone and said, "This is not a rare situation. I think all teachers have seen it in clinical work."

Typical representatives of vancomycin resistance are Staphylococcus aureus and Enterococcus, which will be quite difficult to treat once it occurs. Frontline clinicians will have a dilemma of no medicine available, and can only put the last chance to put them on the drug sensitivity experiment.

"Ask how effective vancomycin is downstairs."

Qi Jing had already picked up his cell phone and dialed Ji Qing's phone, but unexpectedly, not only did he hear the dial tone in the earpiece, but also a familiar ringtone, and the direction was right outside the door.

After a while, the door of the conference room opened, and eight experts who had just left here entered one after another.

As soon as Yan Hong entered the door, her face suddenly darkened, and the whole room was filled with a strange smell of food and cigarettes. The afterglow of her eyes swept back and forth, forcing several experts who were still smoking a big mouthful of cigarettes to pinch off the cigarette butts.

Of course, the most eye-catching thing was Huang Yuhuai who stood in front. He carried a black backpack and quickly found an empty seat and sat down.

"Dad, you're finally here." Huang Xinghua breathed a sigh of relief, looked at the critically ill-aided directors around him, and said in confusion, "Why are everyone else coming?"

“Vancomycin is useless.”

Huang Yuhuai took out a thermos from his backpack and gave himself a cup of hot water. After taking a few sips, he said: "The patient has Red Man Syndrome, and the patient has a superposition of hypotension and high heart rate due to shock. The situation is very bad now. You have to find the right antibiotic as soon as possible."

This passage was like a wake-up call and hit the center of the venue. I thought it would be vancomycin resistance, but I suddenly had toxic side effects.

Huang Xinghua didn't know how many times it was tonight, so he frowned again: "This Gram-positive bacteria has no vancomycin and cephalosporin. Should I use penicillin?"

"Yes, there are only a few drugs for Gram-positive bacteria. Once multiple drug-resistant vancomycin appears, it will be the last killer weapon. Now it's actually..."

"Um?"

The two groups of expert groups looked at each other.

They all feel that they are the one who first grasps the pathogen, but this is not the case in terms of the content of the conversation.

"How do you know it's Gram-positive bacteria?"

Huang Yuhuai was a little strange. After looking at the young man next to Huang Xinghua, he seemed to have guessed something, but he couldn't believe it.

"Just ten minutes before you entered the door, Xiao Qi calculated the pathogen." Huang Xinghua replied, "It's pork streptococci."

Huang Xinghua couldn't believe it.

This is a zoonotic disease, and it is a comorbid disease that has almost never been reported in China. Although there were small outbreaks around the world after being discovered in the United States in the 1970s, only some sporadic veterinarians who actually spread to China will dabble in it.

Even so, the amount of information is pitifully small.

The most famous one is the Streptococcus suis infection that broke out in the United States in 1998, with direct economic losses of more than US$3 million. After that, there will be an outbreak of one or two outbreaks almost every year. Although some people have been infected, it is rarely mentioned in the report.

The reason why Huang Yuhuai knows this bacteria was that there were two streptococci infections in Jiangping six years ago, and tens of thousands of pigs died. Among them, some were infected, and a large number of people were infected.

He discovered the disease of streptococci infectious disease of humans through actual combat. It was only after several months of research and statistics that he discovered the disease course and transmission route of this bacteria.

If it weren't for that time, Huang Yuhuai would never have locked in this bacteria so quickly.

Since it is difficult for me to make a judgment easily, how did this child know? Do you rely on guessing?

Obviously impossible.

Is his ancestral home in Jiangping?

"How do you know about Streptococcus suis?" Huang Yuhuai was very curious about this, and even put down the patient's treatment discussion and asked Qi Jing directly.

Unexpectedly, his son stood up at this time: "Dad, he reads the documents."

"Just kidding, there is no such disease in journals of infectious diseases." Huang Yuhuai naturally knew why there was no report on this. There was no such thing as the Internet at the beginning. "If I want to write, I must be the first one. I haven't started writing. Who can write it?"

"I am a veterinarian, from 95 years."

"Just kidding! Will the veterinarian write about the process of human infection?" Huang Yuhuai didn't believe it at all. Although his voice was not loud, his tone was unquestionable. "Without clinical observation and subsequent research summary, how could he know the complete symptoms and infection routes in this regard? Without symptoms and routes as the basis, what would you use to diagnose it?"

Qi Jing didn't expect that the old man was still so serious. He sighed and could only tell the "truth" in the eyes of everyone: "Actually, it was taught by an emergency department director when he went to the United States to communicate. I heard it very interesting at that time, so I wrote it down."

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Chapter completed!
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