Font
Large
Medium
Small
Night
Prev Index    Favorite Next

Chapter 1774: Shall I try it?

Inside Chencang New Drug Research Institute, Dongyang High-tech Development Zone.

It has been officially launched for several months, and everyone is working hard to carry out scientific research, hoping to conquer Parkinson as soon as possible.

After Chen Cang first proposed the commonalities between Alzheimer's disease and Parkinson's disease, the progress of the entire scientific research work has been greatly improved!

However, scientific research always gives people an illusion!

That is, every breakthrough makes people feel like a historic progress, and they all think they can achieve excellent results.

But the result is... after every breakthrough, I suddenly realized that this matter is more difficult!

To solve problems, factors that need to be considered and studied and subjects are still increasing!

Professor Zhang Mu himself is engaged in Alzheimer's disease research, so when Chen Cang proposed that asparagine endopeptidase enzymes can modify tau proteins to make it more sticky and toxic.

Therefore, drugs that inhibit AEP can often show certain benefits in the treatment of animal models of Alzheimer's disease.

In this way, is there an enzyme that can increase the toxicity of folded α-synuclein?

This question is really complicated!

It can even be said to be like looking for a needle in a haystack.

No one can find an "enzyme" from complex tissues to illustrate that this thing is promoting the pathological α-synuclein after folding?

This requires complex bioengineering!

There was a tense and anxious discussion in the office.

Tedanis said with a frown: "The progress of the enzyme engineering is too slow now. I have not received a precise answer from Professor Considing so far!"

"Every time I talk about cooperation, the other party is looking for various reasons to shirk responsibility."

"Why……"

When everyone heard that Tedanis was so disappointed, they didn't know how to comfort him.

Considine and Tedanis were once very good partners.

But since Tedanis came to China, his reputation has been like a crooked butt in a certain circle, and everyone has avoided it.

To be honest, scientific research is still divided into national boundaries most of the time.

Even if many people are unwilling to admit it, they will find various reasons to convince themselves and others.

For example, now, Chen Cang is indeed the fastest researcher in the Parkinson field, but why are those powerful experts unwilling to join?

Is it because they are stupid and don’t understand?

Of course not!

It’s not that you are powerful, everyone will join you.

A very realistic problem, scientific research is always like a competitive relationship.

As long as you have not developed any research results, no matter how you lead, you will not be successful!

For example, now, experts in the field of enzyme engineering are needed in the research institute.

But it's really hard to find this top expert.

There are so few partners from Tedanis that are willing to come now!

Domestic bioengineering itself is in its infancy, and the research on protein enzymes is really difficult.

Even the simplest enzyme separation and purification uses some biofilm separation technologies retired from the United States five years ago.

These are basic research!

But these basic research determines the superstructure.

No scientific research was created out of thin air.

As the person in charge, Zhang Mu couldn't help but sigh.

The development of domestic medicine is really not just the backwardness of pharmaceutical technology, but because the development of medicine is a comprehensive discipline!

Medicine is not a simple discipline, but a high-end discipline.

It involves many basic disciplines such as physics, chemistry, molecular biology, etc.!

Even the separation and purification of enzyme engineering in a small direction seems extremely difficult at this moment!

For a moment, everyone became quiet.

Yang Lan couldn't help but say, "Why don't we still look for old friends from the Chinese Academy of Sciences?"

Zhang Mu shook his head: "He has similar skills to Yu Shuangyong, so there is no need to look for it. The effect will not be obvious when he finds it."

When Yu Shuangyong heard this, he immediately blushed.

Although what Zhang Mu said was not very respectful, it was a real truth!

It has become a problem to break and separate a small enzyme to find out the key core!

At this time, the door opened suddenly.

Everyone who was thinking was suddenly stunned for a moment, a little stunned, and even was shocked. Everyone was a little unhappy for a moment!

Who is here during the meeting?

Everyone turned around and found that it was Chen Cang who came!

Everyone breathed a sigh of relief.

Seeing that the atmosphere was a little depressed, Chen Cang couldn't help but be stunned: "What's wrong... is this?"

"The atmosphere is so depressing?"

Everyone sighed when they heard the sound.

And Zhang Mu said directly: "Professor Chen, I'm just about to find you, sit down and talk."

Chen Cang nodded, found a seat to sit down, and looked at Zhang Mu: "What's wrong?"

Zhang Mu said to Yu Shuangyong: "Old Yu, please tell me."

Yu Shuangyong nodded and picked up the data in his hand:

"It's like this. We extracted, isolated, and purified the enzymes in the rat nervous system. We want to study them according to Professor Chen's initial thought."

"Asparagine endopeptidase can modify Alzheimer's Tau protein to make it more toxic and adhesion-free. As you said, Parkinson's neurodegenerative lesions with a second only to Alzheimer's disease, we have also begun to isolate and purify the enzymes in Parkinson's rats."

"But... we seem to have encountered some problems. I don't know if it is because of technology or other reasons. In this month, we conducted more than 600 separations, more than 3,000 tests, and tens of thousands of tests. There was no way to find an enzyme that could make the folded α-synuclein more toxic!"

"This is the specific data. We can find only 671 enzymes now, and we can no longer continue!"

After Yu Shuangyong finished speaking, everyone sighed.

Tedanis couldn't help saying, "I found my former friend Professor Considing, but... the other party seemed unwilling to help us!"

Zhang Mu suddenly suggested: "Professor Chen, why don't we... change our direction?"

Everyone nodded one after another.

Since there is no way to break through learning asparagine endopeptidase in Alzheimer's disease in the field of enzymes, maybe we should change our direction, right?

After all...enzyme engineering is really expensive.

In this month, Zhang Mu has invested nearly 30 million yuan in this field, and has gained nothing and was wasted!

This is scientific research, cruel and realistic!

Just when everyone was a little disappointed.

Chen Cang suddenly said, "How about...I'll try it?"
Chapter completed!
Prev Index    Favorite Next